Problem Statement-
How to hit breakpoint of global.aspx or breakpoint in global.aspx not getting hit or application_start is not being hit or global.asax – breakpoint not working
Solution for all above statements are same as below,
- Open the global.aspx file by clicking on it.

How to hit breakpoint of global.png
2. Add space at the end before closing end tag.

Adding space in global.aspx
3. Debug the application now.